Hollie Mershon hit the winning layup with 20.6 seconds remaining to lift Drexel over Utah 46-43 on Saturday in the Women's NIT championship game.
Taylor Wootton scored 16 points, including the 1,000th of her career, and Mershon, finished with 14 points, eight rebounds, three assists and two assists for the Dragons (28-10), who closed a record-setting season with the first postseason title in program history.
Mershon was named the tournament MVP.
Iwalani Rodrigues led Utah (23-14) with 12 points, including a 3-pointer that put the visiting Utes up 43-42 with just under three minutes remaining.
But with Drexel still trailing by one in the final minute, Renee Johnson-Allen got a big steal in the backcourt, and after a timeout, Mershon put the Dragons ahead for good with a driving layup through traffic.