Layshia Clarendon scored 19 points to lead California a 73-63 victory over LSU on Saturday night, sending the Bears to the round of eight for the first time in program history.
Gennifer Brandon had 17 points and 13 rebounds, and Brittany Boyd added 14 points for second-seeded Cal (31-3), which will play Georgia in the Spokane Regional final on Monday night.
Theresa Plaisance had 15 points and 12 rebounds for sixth-seeded LSU (22-12).
The Lady Tigers were in the game until a scoring drought late in the second half ended their chances. They were seeking their first berth in the round of eight since 2008.
Fourth-seeded Georgia beat top-seeded Stanford 61-59 in Saturday's opening semifinal Saturday.