Senior Monica Engelman scored a career-high 27 points and Kansas became just the second No. 12 seed to advance to the round of 16 in the NCAA tournament with a 75-69 upset of fourth-seeded South Carolina on Monday night.
Angel Goodrich added 20 points for the Jayhawks (20-13), who joined San Francisco in 1996 as the only No. 12 seeds to follow up a win in the opening round with another in the second.
Fourth-seeded South Carolina (25-8) was denied in its quest for its 26th win, which would have been the program's most since joining the Southeastern Conference in 1991-92.
Instead, it's Kansas, which lost seven of its last 11 games before the tournament. The Jayhawks move on to Norfolk, Va., where they face the winner of Tuesday's game between Notre Dame and Iowa in the regional semifinals Sunday.
Ashley Bruner and Aleighsa Welch each scored 16 points for the Gamecocks.