Tyrone Garland led four players in double figures with 22 points on 9-of-11 from the field, as La Salle used a hot- shooting performance to dispatch Boise State, 80-71, in first-round action of the NCAA Tournament on Wednesday.
Ramon Galloway totaled 21 points, four rebounds and four assists for the Explorers (22-9), who waited 21 years for another crack at the NCAA Tournament and didn't disappoint thanks to a 63.3 percent effort from the floor.
Sam Mills drained five 3-pointers en route to 15 points and Jerrell Wright added 13 with six rebounds.
The first of three Philadelphia-based programs to take the floor became the first to advance, winning their first tourney game since 1990 and earning a shot at fourth-seeded Kansas State in the West Region on Friday.
"We want to make a run, and we want to show everybody that La Salle can play with the best teams in the country," Galloway said.
Anthony Drmic's game-high 28 points -- including five shots from beyond the arc -- wasn't enough for the Broncos (21-11). Derrick Marks had 14 points, seven boards and five assists, while Ryan Watkins contributed 10 points in defeat.
Garland and Mills connected on back-to-back treys to give the Explorers a 68-56 margin with 7:15 to play, and a runner from Galloway pushed the edge to 72-58 less than two minutes later.
Mikey Thompson hit two free throws and Kenny Buckner added one more to pull the Broncos to 74-66 with 2:36 remaining, and after Wright bricked a pair from the line, a Barnes bucket made it 74-68 with 1:51 left.
Tyreek Duren then missed a layup, and Buckner missed the front end of a 1- and-1 after being fouled when pulling down the rebound.
Garland hit both of his attempts for a 76-68 game, and a tip from Marks after a pair of missed three-pointers by Drmic made it a six-point spread once more.
But Galloway made his last shot and Duren made a pair from the charity stripe to seal it.
"They just got on a roll and put way too much pressure on our offense," Boise State head coach Leon Rice said.
La Salle led 10-6 in the early stages, and the Explorers stretched their advantage to 25-12 thanks to a 12-1 run, ending on a Galloway trey -- the last of his five points in the surge -- with 9:12 on the clock.
Boise State reeled off five straight points, but two baskets from Garland and a slam off the break by Galloway provided a 31-17 lead with under 5 1/2 minutes before intermission.
The Broncos pulled within 35-27 at the break on a Drmic three-point play.
Galloway's shot from long distance opened up a 44-34 edge for La Salle early in the second half, and when Garland and Mills were true from beyond the arc on consecutive possessions, it was a 52-38 game.
Boise State managed to answer triple for triple in the next several minutes, but was unable to reduce its deficit to any meaningful number.
La Salle dropped a 78-76 decision to Seton Hall on March 19, 1992 in first- round action of the East Region, and last tasted victory in the NCAAs on March 15, 1990 in a 79-63 triumph over Southern Miss in the East Region ... Boise State shot 49.1 percent, but only 7-of-18 from beyond the arc, while the Explorers connected on 11-of-21 tries from long distance ... Duren posted just four points and five assists with two steals ... Buckner finished with six points and seven rebounds ... The Broncos fell to 0-6 all-time in the premier March tournament.