Nene has recovered enough from a sore right shoulder and is set to play as the Washington Wizards host the Philadelphia 76ers.
In 42 games this season, Nene has averaged 12.6 points and 6.8 rebounds before missing the Wizards' last two games.
A.J. Price (bruised right thigh) will also play Sunday night. Price, who averages 7.4 points and 4.1 assists in 22.7 minutes per game, missed Washington's last game.
For the 76ers, Royal Ivey will replace injured Nick Young (left ankle sprain) in the starting lineup for the second straight game.