Jordan Adams scored 20 points, four others scored at least 10 points and UCLA never trailed in a 75-59 victory over USC on Sunday.
The Bruins (20-7, 10-4 Pac-12) avenged a 75-71 overtime loss to the Trojans (12-15, 7-7) earlier this season.
Kyle Anderson, Larry Drew II and Shabazz Muhammad all scored 11 points, and David Wear had 10 points and 11 rebounds for the Bruins, who shot 47.2 percent from the field.
J.T. Terrell led USC with 17 points, including 14 in the second half to lead a late Trojans charge. Omar Oraby contributed 11 points and five rebounds.
UCLA came out on fire, making eight of its first 10 shots and racing to a 19-6 lead just over 5 minutes into the game. UCLA kept up that dominance and held a 47-26 lead at halftime.