Kayla McBride scored 19 points and pulled down five rebounds to help No. 2 Notre Dame take a 64-42 win over Cincinnati on Saturday.
Kaila Turner scored 11 points for the Fighting Irish (20-1, 8-0 Big East), who have won their past 15 games. Natalie Achonwa scored nine points with six rebounds and Skylar Diggins added nine points and seven assists.
Kayla Cook scored 12 points for the Bearcats (8-13, 0-8), who have lost eight straight games.
Notre Dame scored the first 10 points of the game and never looked back as the team closed the first 20 minutes with a 13-5 run to take a 37-15 lead into the break.
The Bearcats tried to keep up and used six straight points to get within 16, 39-23, just over two minutes into the second half, but the Irish scored the next 14 points to put the contest away.