Amber Deane had 18 points and 11 rebounds Saturday and No. 22 Dayton routed Butler 82-39 in the Atlantic 10 Conference opener for both schools.
Andrea Hoover and Samantha Mackay had 13 points apiece for the Flyers (13-1), who were playing for the first time since their only loss Dec. 30 against Bowling Green.
Daress McClung and Liz Stratman led Butler (9-7) with 11 points each. Stratman scored 10 in the second half.
The Bulldogs stayed close until midway through the first half, when the Flyers went on a 10-0 run and eventually led 44-22 at halftime.
Butler was playing its first game in the Atlantic 10 after leaving the Horizon League.