Meighan Simmons scored 18 points and pulled down five rebounds as No. 9 Tennessee had an easy time with Missouri, winning 84-39 at Thompson-Boling Arena.
Bashaara Graves had 16 points and eight boards for the Lady Vols (12-3, 3-0 SEC), who received 12 points and 15 rebounds from Isabelle Harrison in the program's largest in-conference margin of victory since a 65-point win over Alabama a little more than two years ago.
Morgan Eye poured in 18 points -- all from beyond the arc -- for the Tigers (12-5, 1-2), who shot just 19.7 percent from the field. Eye set an arena record with 17 three-point tries, snapping the previous mark of 16 by Tennessee's Angie Bjorklund from 2008.
The hosts led 12-3 early on, and Mizzou fell behind 48-21 after 20 minutes of play thanks to its poor shooting.
Graves finished off a three-point play with just over 6 1/2 minutes played in the second half which gave the Vols a 59-26 edge, and Tennessee cruised the rest of the way.