Tierra Ruffin-Pratt had 18 points and nine assists to lead No. 16 North Carolina to an 85-44 win over East Tennessee State on Friday.
Xylina McDaniel added 11 points for the Tar Heels (12-1) in their fifth straight win after nine days off.
Serena Clark and Brianna McQueen each scored nine points for East Tennessee State (2-5), which trailed 41-25 at halftime.
North Carolina finished 6 of 18 from 3-point range, while ETSU made 1 of 13.
However, the Tar Heels were outrebounded 47-39, with Destiny Mitchell grabbing a game-high 10.