James Southerland scored 18 points, Michael Carter-Williams had eight points and a career-high 13 assists, and No. 6 Syracuse beat Colgate 87-51 on Sunday.
It was the 165th meeting between the upstate New York foes, and the Orange (4-0) won their 46th straight against Colgate (3-4).
Carter-Williams, who had six rebounds and just one turnover, missed the only shot he attempted in the first half. But he assisted on nine of the Orange's first 10 baskets, giving him a real shot at challenging the school record for assists in a game.
Sherman Douglas had 22 against Providence in January 1989. Pearl Washington had 18 against St. John's during the 1983-84 season, and Douglas was among five players to notch 14 in a game.
Brandon Triche finished with 15 points, freshman Dajuan Coleman had a career-high 12 points, and Rakeem Christmas had 10 points and nine rebounds for the Orange.