Aaryn Ellenberg scored 19 points Saturday and No. 12 Oklahoma won its opening game, beating Creighton 69-48.
Whitney Hand had 14 points and eight rebounds for the Sooners, who shot 48 percent from the field. Ellenberg was 8 for 12 from outside, including 3 for 4 from 3-point range.
Creighton led in the early going but Oklahoma took control midway through the first half, and led by double digits in the game's last 28 minutes.
Ally Jensen was the only player in double figures for the Bluejays, scoring 13 points.