Zach Randolph had 15 points and 14 rebounds in the Memphis Grizzlies' 93-85 win over the Houston Rockets.
Rudy Gay added 21 points and seven boards, while Mike Conley chipped in 14 points for Memphis, which has won four straight on the heels of its season- opening loss to the Los Angeles Clippers.
Chandler Parsons tallied 19 points, while James Harden registered 18 points, but on just 4-of-18 shooting for the Rockets, who dropped their first road game in three chances.
"I just took it as a challenge," Tony Allen said of defending Harden. "And we had great guys step up and put fresh bodies on him."
Omer Asik recorded 10 points and 13 boards and Jeremy Lin had 15, including a fast break layup which pulled the visitors within 87-85 with 2:23 to play, in defeat.
Memphis, though, netted the final six points of the contest.
Conley nailed a 3-pointer following the Lin layup, and after Parson's runner clanked off the rim, Gay's putback made it 92-85 with 1:03 to go.
The Grizzlies snatched three offensive rebounds on the possessions with Gay tallying the last two.
Gay then split a pair from the line with 20.9 left to account for the final margin.
The Rockets led 24-17 after a quarter of play and took a 46-42 advantage into the break.
Memphis outscored Houston, 27-22, in the third and held a slim 69-68 edge going into the fourth.
Jerryd Bayless' layup capped 16-4 Grizzlies run, which gave the hosts an 87-75 margin midway through the final frame, before Houston countered with a 10-0 spurt to get within two.
"We had 20 turnovers, and they had 18 offensive rebounds," Houston head coach Kevin McHale said. "That's too much. We have got to control that."
Memphis held a 48-34 points in the paint advantage ... The Grizzlies had a 21-5 lead in fast break points ... Houston turned the ball over 20 times, which led to 27 points for Memphis ... The Grizzlies committed just nine turnovers.