Substitutes Martin Caceres and Paul Pogba both scored as Juventus extended its Serie A unbeaten streak to 47 games and opened a three-point lead over Napoli with a 3-0 win Saturday.
Juventus and Napoli started the fixture at Juventus Stadium even on 19 points, and were on equal ground until the final 10 minutes of normal time, when goals from Caceres and Pogba changed the match.
Caceres was on the pitch for only four minutes when he opened the scoring just 10 minutes from time and Pogba followed in the 82nd, just six minutes after he stepped on the field.
Juve has not lost since the next-to-last match in the 2010-11 season, and sent Napoli to its first defeat of the current campaign.
Napoli had the best chance before the first goal, but Edison Cavani caught the inside of the right post off a free kick in the 27th minute.
Caceres separated the teams in the 80th, when he ran under a corner kick from Andrea Pirlo and powered a header from six yards to the middle of the goal out of the reach of Napoli goalkeeper Morgan De Sanctis.
De Sanctis was helpless again two minutes later despite a diving attempt as an impressive volley from Pogba from 25 yards took one hop before nestling inside the right post in the 82nd minute.
Lazio 3, AC Milan 2
Rome, Italy - Miroslav Klose scored his sixth goal as Lazio built a three-goal lead and held on for a 3-2 Serie A win over AC Milan on Saturday at the Stadio Olimpico.
Hernanes, his fifth of the season, and Antonio Candreva scored in the opening half for Lazio, and Klose put the hosts up three goals five minutes into the second half as he continued his great early-season form.
Milan rallied behind goals from Nigel De Jong and a fifth of the season from Stephan El Shaarawy in the 61st and 79th minutes, respectively, but it was not enough to rescue a point in Rome.
Lazio won its third straight and sits four points off the pace of undefeated leader Juventus in third place. Milan lost for the fourth time in its last six league matches and is 15 points off the pace in 13th place.