South Florida (2-4, 0-2 Big East) at No. 16 Louisville (6-0, 1-0), 3:30 p.m. (ABC)
Line: Louisville by 8.
Series Record: Louisville leads 5-4.
WHAT'S AT STAKE
South Florida is trying to end a four-game losing streak. Louisville aims to continue its best start since 2006 (8-0), the last year it also began 2-0 in the Big East. The Cardinals also seek momentum for next week's conference game against No. 21 Cincinnati (1-0).
Louisville WR DeVante Parker vs. South Florida CBs George Baker and Kayvon Webster. Parker leads the Cardinals with 319 yards on 15 receptions, a 21.3-yard average per catch. He'll face a Bulls secondary seeking their first interception this season, the only Football Bowl Subdivision team without one. Webster is USF's fourth-leading tackler (39), while Baker stands ninth (22).
PLAYERS TO WATCH
USF: QB B.J. Daniels. Second in Big East in total offense (296.8 yards per game), he has passed for 1,504 yards and 10 touchdowns. His 250.7-yard average ranks third in the conference.
Louisville: QB Teddy Bridgewater. The sophomore has been stellar on third down this season, completing 31 of 45 passes for 411 yards, 24 first downs, three touchdowns and one interception. He's 2-for-2 on fourth down.
FACTS & FIGURES
South Florida has lost 10 of 11 Big East games dating back to last season. ... The Bulls haven't forced a turnover in three games. ... Louisville is playing its first home game in 35 days and the first of three in a row at Papa John's Cardinal Stadium, where it's 3-0 this season. ... Last week's victory at Pitt evened the Cardinals' overall Big East record at 25-25. ... RB Senorise Perry has a team-high 582 rushing yards and nine touchdowns, including four last week against the Panthers.