Bolton has fired manager Owen Coyle after the club's poor start to the second-tier League Championship following its relegation from the Premier League.
Bolton is 18th in the 24-team standings with 11 points from 10 games.
Bolton chairman Phil Gartside said Tuesday "it is the right time for a change."
Coyle was praised for the way he supported Fabrice Muamba after the midfielder suffered an on-field cardiac arrest during an FA Cup match at Tottenham in March.
But his team's 11-year stint in the country's top division came to an end and it has won just three matches this season.