Arizona Cardinals head coach Ken Whisenhunt announced Monday that running back Ryan Williams will miss the rest of the season with a shoulder injury he suffered against the St. Louis Rams last Thursday.

A second-round pick out of Virginia Tech in the 2011 draft, Williams missed all of his rookie campaign last year with a ruptured patellar tendon in his right knee.

The 22-year-old tallied 164 yards rushing on 58 carries and caught seven balls for 44 yards this season.