Nebraska coach Bo Pelini left the stadium in an ambulance at halftime of the Cornhuskers' 42-13 victory against Arkansas State on Saturday.
Taylor Martinez threw two touchdown passes to Kenny Bell for Nebraska (2-1), and Ameer Abdullah ran for a career-high 167 yards and two scores, filling in for the injured rex Burkhead.
There was no immediate word on the condition of the 44-year-old Pelini. Defensive coordinator John Papuchis was acting head coach in the second half.
The Huskers' defense bounced back from a shoddy defensive performance in a 36-30 road loss to UCLA, holding Arkansas State's high-scoring offense to two field goals. The Red Wolves' only TD came when Qushaun Lee recovered Taylor Martinez's fumble in the end zone.
Nebraska limited the Red Wolves to 286 yards, 89 in the second half.
Martinez was 13 of 14 for 180 yards.