Abdelaziz Barrada scored the match-winner in the 75th minute as Getafe shocked Real Madrid, 2-1, on Sunday at the Coliseum Alfonso Perez in La Liga.
Gonzalo Higuain fired Real in front after 26 minutes, but Juan Valera pulled a goal back in the 53rd and Barrada followed in the 75th as Getafe pulled off a huge upset in the second week of the season.
Madrid tied its opener against Valencia last week, 1-1, and lost the first leg of the Spanish Supercup to Barcelona, 3-2, midweek. Higuain converted a pass from Angel Di Maria inside the half-hour mark as Real eyed its first win.
Barrada set up the first goal with a pass to Valera, who scored to the bottom- left corner. Adrian Colunga provided the final pass on the winning goal, and Barrada made no mistake from 16 yards with a high finish to the middle.
Fabio Coentrao received his marching orders for a straight red from the bench, as Real Madrid was left frustrated and on one point - already six behind rival Barcelona - after just two weeks.
Getafe won its first match of the season.
Barcelona 2, Osasuna 1
Navarra, Spain - Lionel Messi scored two goals in a five-minute stretch late in the second half as Barcelona rallied for a 2-1 win over 10-man Osasuna on Sunday at Estadio El Sadar in La Liga.
Messi opened the season with a brace in a 5-1 win over Real Sociedad, and with his club on the verge of a surprise loss, rescued a win with goals in the 75th and 80th minutes.
Joseba Llorente put Osasuna in front in the 17th minute, and Nino almost added a second on a breakaway in the 71st but slotted just wide of the right post.
Messi took over from there, slipping a shot into the bottom left from the edge of the six-yard box in the 75th for his first goal and a shot from 16 yards to the bottom left in the 80th.
Valencia 3, Deportivo 3
Valencia, Spain - Abel Aguilar scored a brace to cancel out two goals from Roberto Soldado, and Pizzi converted the tying penalty kick in the 76th minute as Deportivo rallied for a 3-3 draw against Valencia on Sunday.
Roberto Soldado scored a brace inside the half-hour mark and Sofiane Feghouli also scored in the first half as Valencia built two two-goal leads in the first half at the Mestalla.
But Aguilar scored his second goal in the 59th to pull Deportivo within one goal for the second time, and Pizzi converted from the spot after Ricardo Costa earned his marching orders.
Valencia held on for a point with 10 men, and sits on just two points after its first two matches. Valencia tied Real Madrid in its opener. Deportivo won its opener, and has four points.
Granada 1, Sevilla 1
Granada, Spain - Alvaro Negredo scored just before halftime as 10-man Sevilla escaped Los Carmenes with 1-1 draw against Granada in La Liga on Sunday.
Diego Lopez was sent off in the 34th minute, but although Guillherme Siqueira missed the ensuing penalty, Moreno Mikel Rico put home a second chance to give the hosts a lead.
Negredo split the points when he scored two minutes before half,.