Top-seeded Sara Errani cruised past Edina Gallovits-Hall of Romania 6-1, 6-1 in the first round of the Italiacom Open on Tuesday, while five-time champion Anabel Medina Garrigues lost to a wild-card entry.
Errani, a French Open finalist last month who is ranked a career-best No. 9, won this clay tournament in 2008.
Medina Garrigues, who won titles at the Country Time Club in 2001, 2004-06 and 2011, lost 6-1, 6-3 to Italy's Maria Elena Camerin.
In other matches, second-seeded Roberta Vinci beat fellow Italian Karin Knapp 6-2, 6-2; third-seeded Julia Goerges of Germany defeated Akgul Amanmuradova of Uzbekistan 6-4, 7-6 (8); and fifth-seeded Carla Suarez Navarro of Spain beat Sacha Jones of Australia 6-4, 6-1.
Also, 18-year-old Laura Robson of Britain routed Valentyna Ivakhnenko of Ukraine 6-1, 6-0.