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The Phillies have made Petco Park their home over the past few years. That goes double for San Diego-born starter Cole Hamels.

Hamels aims to pitch Philadelphia to a 13th straight victory in San Diego as the Phils play the second of a four-game series against the Padres.

The 28-year-old Hamels owns a 3-1 career record at Petco Park with a 1.23 earned run average and picked up a victory there last season with eight scoreless innings. He is 6-2 with a 2.28 ERA in 11 career meetings against his hometown club.

Hamels has struck out 19 over his first two starts of the season, losing his season debut on April 9 before beating the Mets on Sunday. The left-hander gave up two runs over seven innings, scattering six hits and walking one while fanning 10.

The Phillies turn to Hamels looking to avoid their first loss in San Diego since Aug. 16, 2008. They ran their winning streak at Petco Park to 12 in a row with last night's 2-0 win. Philadelphia has won 11 of 12 and 18 of its past 21 overall versus San Diego.

Vance Worley struck out a career-high 11 over seven strong innings to get last night's winning, scattering four hits. Juan Pierre and Hunter Pence scored both runs for a Philadelphia club that had lost four of six.

"I definitely want to strike guys out and today they were just swinging and missing," said Worley.

San Diego rookie Joe Wieland suffered the loss despite giving up just one run on five hits and one walk while striking out seven over six frames. The Padres had just four hits in their seventh loss in eight tries.

"This guy has less than two weeks in the major leagues at 22 years old and he's showing some good signs at a really, really infant stage," Padres manager Bud Black said about Wieland.

Edinson Volquez will make his fourth start of the season and hasn't factored into the decision of his past two outings since his season-opening loss on April 5. The right-hander allowed four runs on six hits and five walks over five innings versus the Dodgers on Sunday, giving him 12 walks and 17 strikeouts in his 17 innings.

The 28-year-old has dominated the Phillies in two career starts, giving up one run over 12 1/3 innings with 16 strikeouts while winning both games.