Sale allowed a one-out double to Zack Cozart in the first inning and a single to Cozart leading off the fourth. Sale, who had allowed eight runs in 7 1-3 innings in his previous two starts, is moving to the rotation following two seasons in the bullpen.
Reds starter Homer Bailey gave up three hits in four scoreless innings.
Each team finished with four hits. Wilson Valdez drove in the only run with a bunt single in the ninth inning.