Luis Scola scored 23 points and Goran Dragic 87 rout of the Bobcats.
Jordan Hill had 14 points while Samuel Dalembert finished with 12 and 10 rebounds for the Rockets, who were without starting guards Kyle Lowry and Kevin Martin. Houston was coming off of Tuesday's victory over Oklahoma City and has won three of four after a five-game slide.
Derrick Brown scored 15 points to pace the Bobcats. They defeated New Orleans on Monday but fell to an NBA-worst 6-35 with Wednesday's loss.