Earlier this spring, Lester pitched two innings in a 25-0 win over Northeastern and 2 2-3 innings in a 'B' game against Minnesota.
Against the Orioles, the left-hander walked four and struck out two. The only hit he gave up was an RBI single to Adam Jones in the first inning.
Pedroia's two-out double off Dana Eveland in the second gave Boston a 3-1 lead.
Eveland gave up three runs — one earned — and six hits in two innings. In two spring starts, both against the Red Sox, he has allowed eight hits in four innings.
The Orioles finished with three hits.