Updated

Cuban defector Yoenis Cespedes homered, walked and singled in his first major league game, leading the Oakland Athletics to a 6-3 win over the Cincinnati Reds on Saturday.

Manny Ramirez went 0 for 3 in his return to the lineup after missing a few days because of lower back stiffness.

Cespedes walked on five pitches in his first at-bat against Johnny Cueto. He singled in his second at bat and crushed a long home run off Jeff Francis after fouling off several pitches.

Bartolo Colon pitched four innings, allowing one run on four hits in his second spring start. He struck out four.

Colon's first start is scheduled for March 29 when the A's play Seattle in Japan.

Cueto, the Reds opening day starter, allowed three runs and five hits — two earned — in two innings.