Kris Joseph scored a game-high 21 points as No. 69 victory over Connecticut to season title.
Saturday's narrow decision also marked a milestone for Orange head coach Jim Boeheim, who earned his 400th career Big East conference win.
Fab Melo added 11 points and nine rebounds for Syracuse (29-1, 16-1 Big East), which won its ninth straight game.
Jeremy Lamb netted 19 points to lead the Huskies (17-11, 7-9), who lost for the eighth time in 11 games. Andre Drummond contributed 15 points and 13 rebounds in a losing effort.