Southern California head coach Kevin O'Neill announced on Friday that forward Dewayne Dedmon was diagnosed with a torn medial collateral ligament in his left knee as is likely out for the remainder of the season.
"I feel for Dewayne and our team," said O'Neill. "Obviously it is another huge blow for us as we move forward."
Dedmon suffered the injury in Thursday's game when a Colorado player drew a charge and fell back on Dedmon's knee, causing a hyperextension of the leg.
The seven-foot sophomore is the fifth USC player to suffer a season-ending injury, joining Jio Fontan (knee), Aaron Fuller (labrum), Evan Smith (labrum) and Curtis Washington (labrum).
In 20 games this season, Dedmon averaged 7.6 points and 5.5 rebounds.