Inter Milan will attempt to get back to match winning streak halted in the Coppa Italia by Napoli in midweek.
The 2-0 setback prevented Inter from reaching the semifinals of the competition for the first time in nine years, but Claudio Ranieri's men will turn their attentions back to the league in an effort to continue their climb up the Serie A table.
The Nerazzurri's 2-1 win over Lazio last weekend allowed Inter to climb to fourth in the league and just six points back of leaders Juventus, which faces third-place Udinese on Saturday.
Juve secured a place in the last four of the Coppa Italia by handing Roma a 3-0 defeat on Tuesday, and the club enters the weekend one point clear of second-place AC Milan.
The Rossoneri has won four of its last five games in the league and manager Massimiliano Allegri will be facing his former side Cagliari at the San Siro on Sunday with the visitors riding a three-game unbeaten streak.
Lazio slipped to fifth with its 2-1 loss to Inter last weekend and the club will try to reverse its fortunes at Chievo on Sunday with the Biancoceleste having won only one of its last five games in the league.
Roma sits three points back of Lazio and will be trying to keep the pressure on its rivals with a win at home against Bologna, while Napoli has fallen to seventh in the table after two league wins in its last six matches and travels to Genoa.
The other match on Saturday features mid-table sides Parma and Catania getting together with the two teams separated by one point.
Palermo snapped a six-game winless streak with a 5-3 win over Genoa and will look to pick up a second victory in a row at home against last-place Novara.
Fiorentina has won one of its last six matches and hosts a Siena side that sits four points clear of the drop zone and Cesena hosts Atalanta with the home side having lost four of its last five.