Holding a 2-1 lead, Stamkos' game-winner came at 10:05 of the second period when the star winger got a perfect feed from Vincent Lecavalier in the left circle and snapped a quick shot past Mason for a 3-1 advantage.
Columbus showed resiliency and came up with an answer just over two minutes later when Nash picked up a loose puck in the neutral zone and raced up the right wing into Lightning territory. He dished to Jeff Carter, who fired one that was stopped by Garon, but Nash picked up the rebound, brought it around the back of the net and stuffed it into the other side to make it 3-2.
Columbus pulled Mason in favor of the extra attacker with a minute to go in regulation, but was unable to generate any significant offensive pressure.
Tampa Bay opened the scoring at 7:27 of the opening stanza when Teddy Purcell chased down a loose puck behind the net and found Jones, who chipped it home from in close.
The Lightning made it 2-0 at 18:12 of the first period when Stamkos controlled the puck in the left circle and sent a cross-ice pass to a wide open Brewer, who slapped it through traffic and past Mason from the right point.
The Blue Jackets answered at 5:43 of the second period on the power play when Umberger accepted a nice saucer pass from Prospal in front of the net, took it around behind and stuffed it into an open cage.
Prior to the game, Prospal was honored for reaching 1,000 games played in his career...Saturday marked the first meeting of the season between the teams...Lightning defenseman Matt Gilroy was scratched with a lower-body injury...Carter had his four-game goal scoring streak snapped...Tampa Bay failed on three power play opportunities, while the Blue Jackets went 1-for-5 with the man advantage...Columbus will face the St. Louis Blues on Sunday, while the Lightning will head west to tangle with the San Jose Sharks on Wednesday.