Alyssa Thomas had 18 points to lead four players in double figures and No. 5 Maryland beat George Mason 78-50 on Sunday.
Laurin Mincy scored 15 points, Lynetta Kizer had 14 and Anjale Barrett 13 for the Terrapins (11-0).
Coming off a team-record 75-point win over Delaware State on Thursday, the Terrapins trailed briefly early, but built a 24-point lead by halftime.
Maryland scored the first 10 points of the second half and Barrett's jumper at the 15-minute mark put the Terrapins up by 36. Maryland eventually led by as many as 40 points and George Mason got no closer than 28 the rest of the way.
Taleia Moton led the Patriots (6-3) with 16 points and Janaa Pickard added 12.
Maryland, now 5-0 all-time against George Mason, shot 46 percent from the field for the game and outrebounded George Mason 59-33. The Patriots made just 17 of 71 field goal attempts.
George Mason hit three of its first four shots, including two 3-pointers, and led 8-4. Led by Thomas and Alicia DeVaughn, the Terrapins went on a 12-0 run and outscored the Patriots 40-12 over the remainder of the half.
After Moton's three-point play pulled George Mason within 21-13, the Patriots went nearly 9 minutes without scoring and trailed by as many as 27 points.
With their jump shots not falling, the Terrapins pounded the ball inside, scoring 28 of their 44 first-half points in the paint, including 12 off offensive rebounds. Maryland made 17 of 34 shots and outrebounded George Mason 31-12 in the half.
Unable to sustain their early solid shooting, the Patriots made just 7 of 33 shots in the first half.