The best-of-five championship round will be staged indoors on red clay at Seville's Olympic Stadium from December 2-4.
Argentina will feature former U.S. Open champ Juan Martin del Potro, former Wimbledon runner-up David Nalbandian, Juan Ignacio Chela and Juan Monaco. Del Potro, Nadal and Ferrer represent three of the top-11 players on the planet.
The Spaniards are captained by former French Open champion Albert Costa, while Tito Vazquez guides the capable Argentines.
Spain is 3-0 all-time versus Argentina, including a victory in the 2008 final in Mar del Plata, where the Argentines were the hosts. The Spaniards have won four of the last 11 Davis Cup titles, while Argentina is still seeking that elusive first-ever championship.