Scott, whose caddie Steve Williams used to work for Woods and recently made racially-inflammatory comments about his former boss, and K.J. Choi trounced Woods and Steve Stricker, 7 & 6 in a foursomes match Thursday at the Presidents Cup.
"Unfortunately, they got off to a quick start and we just couldn't keep up," Woods said in a televised interview.
While there were no incidents related to Woods and Williams, the International side handed Woods his worst loss in team competition in either the Presidents Cup or Ryder Cup.
The margin of victory was the most lopsided in Presidents Cup history.
Woods and Stricker didn't make a birdie at Royal Melbourne and didn't win a hole on Thursday. They were American captain Fred Couples' best team after posting a 4-0 record in team play at the last Presidents Cup two years ago.
The Internationals won the second, fifth, sixth, seventh and ninth holes to make the turn 5-up. They captured the 11th and 12th and the shell-shocked Americans were sent home early.
"The golf course is so difficult, it's hard to make up shots," Woods said on TV.