Hines has been out of practice all week with an ankle injury and might miss a game for the first time since 2007.
Should he be unable to go, Emmanuel Sanders will likely get the starting nod.
Ward has 258 yards and two scores with 26 catches in seven games this season.
In other injury news for Pittsburgh, linebackers James Harrison (eye) and Jason Worilds (quadricep), tackle Chris Hoke (neck) and guard Doug Legursky (toe) are all out while linebacker James Farrior (calf) is also questionable.
The Steelers (5-2) host the Patriots (5-1).