Burres (1-0), making his first appearance in the majors this season, gave up one run on five hits to pick up the win. The southpaw went 4-5 with the Pirates over 20 appearances (13 starts) in 2010.
Pittsburgh, which snapped a five-game skid, lost outfielder Andrew McCutchen in the first inning. Ryan Dempster threw a fastball that hit the top of McCutchen's left hand. He was able to run the bases but did not take the field in the bottom half of the inning.
Alex Presley moved from left field to center and Tabata came off the bench to play left. Tabata did not start because of an injured wrist.
Carlos Pena homered for the Cubs, who have lost two in a row since a two-game winning streak.
Dempster (10-11) gave up three runs on seven hits over 6 1/3 innings to take the loss. He struck out nine and walked one in his third straight defeat.