Buffalo blew a three-goal lead against the masters of the postseason comeback.
Tyler Ennis wouldn't let the Sabres blow the game.
Ennis scored off a rebound 5:31 into overtime Friday night to give Buffalo a 4-3 victory over the Flyers and a 3-2 lead in the first-round series.
Ennis was determined to score the winner and got the chance in OT. Mike Webber set up the goal when he fired a slapper that knocked off Michael Leighton's pad. Ennis swooped in from the right side and scored his second goal of the game.
The Sabres survived after blowing a 3-0 lead and can advance to the Eastern Conference semifinals with a victory in Game 6 on Sunday in Buffalo.
"This is definitely a great place to play," Ennis said. "Any time you can silence the crowd like that, it's an awesome feeling."
Ennis opened the scoring in the first period, and Thomas Vanek and Marc-Andre Gragnani also scored in the period to chase Flyers starting goalie Brian Boucher. Leighton, who led the Flyers to the Stanley Cup finals a year ago, was flawless until overtime.
James van Riemsdyk, Andrej Meszaros and Danny Briere scored for the Flyers.
The Flyers, the No. 2 seed in the East, are missing Jeff Carter and Chris Pronger and are on their third goalie of the series. Their biggest problem could come Sunday with the Sabres poised to send the defending conference champions home.
Ryan Miller made 36 saves for Buffalo.
Staked to the early lead, it seemed over for Flyers. Miller has two 1-0 victories in the series and appeared to again stump the Flyers. Not for long.
After van Riemsdyk and Meszaros scored in the second, Briere stuck it to his former team when his backhander off a behind-the-net feed from Mike Richards tied it at 3.
The rally ended there.
Ennis pounded the winner past Leighton, who made only his second appearance for the Flyers this season.
"I liked the fact that we were able to regroup," coach Lindy Ruff said. "I told the team that we just needed to relax. We needed to make more plays, and we did a tremendous job."
Stuck in a 3-0 hole, the Flyers felt at home.
After all, last season they trailed Boston 3-0 in the Eastern Conference semifinals and won the series. The Flyers won Game 7 after trailing 3-0.
"We can't hang our heads," Briere said. "We were in a worse position last year, so if there's a group of guys that can do it, I believe in this group here."
Like last year's Game 7 in Boston, van Riemsdyk struck first. With Miller a few feet in front of the crease, JVR punched the puck into the empty net to end Miller's shutout streak.
Meszaros then scorched a liner from the point to make it 3-2.
Flyers fans busted out the derisive "Miller! Miller!" chants. The Flyers outshot the Sabres 15-5 in the second and appeared in control.
Hard to believe considering the damage Buffalo inflicted in the first.
For the second time in the series, the Sabres chased a Flyers goalie after taking a 3-0 lead. In Game 2, it was rookie Sergei Bobrovsky. On Friday, Boucher was yanked after allowing three goals on 11 shots.
Leighton got the call, capping one of the improbable rides of any recent Flyer. He started for the Flyers in the Stanley Cup finals, signed a two-year deal in the summer, then hurt his back and spent all but one game in the minors.
Improbably, he'll likely start Game 6.
Boucher allowed two of the softest goals of the season only 1:27 apart early in the first. Ennis and Vanek each scored after Boucher let the puck knock off his leg and into the net.
Gragnani banked the puck off the post past a surprised Boucher on a power play for a 3-0 lead late in the first.
That was all for Boucher, who knew he blew his shot to remain the No. 1 goalie. He whacked a row of sticks with his goalie stick, kicked the sticks and tossed his helmet inside the tunnel leading to the locker room.
"I'd very much like to redeem myself," Boucher said. "Like I said, it was my responsibility tonight. I take ownership in that. To put your team in a hole like that, they didn't deserve that."
Leighton stopped the final 18 shots in regulation and he might just yet bail out the Flyers again in the playoffs.
As usual, coach Peter Laviolette refused to tip his hand.
The Flyers played without winger Carter and defensman Pronger. Carter was knocked out of Game 4 after he hurt his right knee in a collision, and Pronger, who appeared close to a return, is still out with a broken right hand.
The Sabres suffered a blow when they lost forward Jason Pominville in the first period.
Pominville, who scored the only goal in Game 4, slammed down his stick and helmet and hopped on his right leg off the ice. He appeared to get sliced in the back of his leg after a collision in the corner of the Sabres' zone.
"It doesn't look too good for him," Ruff said. "We'll know more about that tomorrow."
NOTES: Leighton won his only start for the Flyers this season. ... A puck shattered a pane of glass during warmups.