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Hideki Matsui homered to help the Athletics break out of a season-long offensive slump and Brandon McCarthy pitched into the eighth inning in Oakland's 5-3 victory over the Minnesota Twins on Sunday.

McCarthy (1-0) allowed two runs and nine hits with five strikeouts in 7 1-3 innings and Josh Willingham also went deep for the A's, who took two of three from Minnesota in the Twins' first home series of the season. Brian Fuentes earned his third save.

Justin Morneau had three hits and an RBI for the Twins and Jim Thome hit his first homer of the season. But their three-run eighth was too little, too late in another slow day for the offense.

Scott Baker (0-2) gave up four runs on seven hits with two walks and five strikeouts in five innings.

Landon Powell had two hits and an RBI and the A's scored four runs in the sixth inning — they scored four total in their previous four games — to take a 5-0 lead.

The way the Twins had been swinging the bats, that lead seemed insurmountable. But McCarthy gave up a single to Denard Span and a double to Joe Mauer to start the eighth. After Morneau drove in Span with a groundout, Thome launched his two-run homer off lefty Jeremy Blevins over the 36-foot high wall behind the center-field fence to make it 5-3.

Fuentes, who has not allowed a run to the Twins in seven career appearances, slammed the door in the ninth to close it out.

Oakland entered the game with just 24 runs in eight games, the third-fewest in the American League. Yet even they were ahead of the Twins, who had 21.

Twins manager Ron Gardenhire pulled out all the stops to try and jump-start his struggling lineup, moving Michael Cuddyer from right field to second base and giving Mauer a rare day game behind the plate.

On paper it looked quite formidable with Mauer hitting second followed by Morneau, Thome, Delmon Young, Jason Kubel and Cuddyer against a right-handed pitcher, ideal for Minnesota's lefty-heavy lineup.

But McCarthy chewed them up all game long, pounding the strike zone and recording 11 groundouts.

The series featured both good pitching and anemic offense, with the teams combining to score 12 runs in the three games. Runs were at such a premium that when Matsui's homer slammed off the scoreboard on the facing of the second deck in right-center, the hometown fans let out a groan as if the game had ended right there.

Willingham led off the sixth with a towering home run to left field that traveled an estimated 427 feet. Kevin Kouzmanoff and Cliff Pennington added sacrifice flies and Powell had an RBI double to make it 5-0.

NOTES: Thome's two RBIs gave him 1,629, moving him past Harold Baines for 29th on the career list. ... Mauer received his 2010 Gold Glove before the game. ... The Twins also honored the University of Minnesota-Duluth men's hockey team, which won the national championship Saturday night with an overtime victory against Michigan. ... Ryan Sweeney got his first start of the season for the A's, going 1 for 3 with a double while playing right field.