Updated

Another game, another loss and more miscues for the winless San Francisco Giants.

The defending World Series champions lost 4-3 to the rival Los Angeles Dodgers on Friday night, committing two errors to go with the three they had in a 2-1 loss in the teams' season opener a night earlier.

"That's not what you thought would happen opening up here. We're just shooting ourselves in the foot," manager Bruce Bochy said. "It's a tough way to lose two close ballgames."

Rafael Furcal singled in the go-ahead run to highlight a three-run sixth inning for the Dodgers, allowing new manager Don Mattingly to match the 2-0 start of mentor and retired Los Angeles skipper Joe Torre in 2008.

Giants starter Jonathan Sanchez (0-1) gave up four runs — two earned — and seven hits in 5 2-3 innings, struck out eight and walked three.

"Right now we're not clicking well offensively. They're pitching well, too," Bochy said. "(Chad) Billingsley had good stuff, so in games like this you need to play well defensively. And right now we're not. That's two games in a row that mistakes have hurt us."

The Dodgers rallied from a two-run deficit with three runs in the sixth. James Loney's sacrifice fly scored Matt Kemp, who singled and went all the way to third on Marcus Thames' slow grounder to third base.

Rod Barajas followed with a single and Aaron Miles reached on an infield hit to third baseman Pablo Sandoval, whose throw to first got past rookie Brandon Belt for an error, putting runners at second and third.

"I tried to rush it. I was supposed to hold the ball in that situation," Sandoval said. "We've been trying to rush a little bit more and trying too hard. I know we have offense, but we have to keep working hard on the defense."

Hector Gimenez batted for Billingsley and followed with a dribbler to the left of the mound and Sanchez misplayed it for an error, allowing Barajas to score the tying run. Guillermo Mota relieved Sanchez and gave up Furcal's RBI single that gave the Dodgers a 4-3 lead.

"I went too fast on that play and I just missed it. That cost us the game," Sanchez said. "But that's baseball. We're not perfect. We're going to make errors."

Billingsley (1-0) allowed three runs and five hits in six innings, struck out four and walked one. The right-hander, who signed a three-year contract Wednesday, improved to 5-1 with a 1.37 ERA against the Giants at home since 2008.

Jonathan Broxton pitched a perfect ninth to earn his second save.

Belt hit a three-run homer to center on a 2-0 pitch from Billingsley in the fourth to give the Giants a 3-1 edge. The 22-year-old first baseman got his first major league hit Thursday.

The Dodgers' first run came on Kemp's ground-rule double to left-center with two outs in the third.

NOTES: Giants LHP Barry Zito threw 35-40 pitches, two days after he was involved in a car accident in West Hollywood. "I was encouraged by it. I was expecting a stiffer guy," pitching coach Dave Righetti said, adding that Zito would be re-evaluated on Saturday. He remains possible to make his scheduled start in the series finale Sunday. ... Giants 2B Freddy Sanchez got a one-year contract for the 2012 season worth $6 million. ... Dodgers INF Juan Uribe sat out because of swelling in his elbow after getting hit by a pitch Thursday. ... A male fan in the ninth row got hit in the right temple by Buster Posey's flying bat as the Giants catcher struck out to end the seventh. After being tended to by medics, the man held up the bat as the crowd cheered. The bat sailed over owner Frank McCourt's box seat in the third row.