Eric Griffin scored a career-high 23 points, grabbed eight rebounds and blocked three shots to help Campbell hold off North Florida 76-66 on Saturday night.
The Fighting Camels (11-10, 5-6 Atlantic Sun Conference) ended a four-game road losing streak and defeated the Ospreys for the eighth time in the last 10 games in the series.
Campbell closed the first half on a 6-0 run to lead 37-30, then increased the lead to 13, at 51-38.
North Florida (8-14, 5-6) used a 14-4 run, capped by two 3-pointers by Jerron Granberry, to get to 55-52 with 7:50 to go.
Campbell responded with a 16-4 run, including eight points from Anthony Horton, to pull away.
Junard Hartley added a career-high 16 points while Horton scored 12 of his career-high 14 in the second half.
Parker Smith scored 21 to lead the Ospreys, hitting 4 of 8 3-pointers and 9 of 9 free throws.