Alioune Diouf scored 19 points to lead James Madison to a 78-57 victory over Radford on Saturday night.
Diouf hit four of the Dukes' 11 3-pointers and they outrebounded Radford 48-32 behind 13 boards from Rayshawn Goins.
James Madison (7-3) dominated from the start, taking a 13-3 lead on Diouf's layup with 12:42 left in the first half.
Diouf hit two 3-pointers in a span of 2 minutes and Trevon Flores' jumper gave the Dukes a 26-8 advantage with 8:19 remaining.
The lead reached 42-21 on Devon Moore's layup with 18:08 left to play in the game.
Julius Wells was the only other James Madison player in double figures with 10 points as 11 Dukes scored.
Blake Smith scored 12 points to lead Radford (2-7), which has lost seven consecutive games.
The Highlanders were 5 of 24 from the field in the first half (20.8 percent) and finished at 33.3 percent (16 of 48).