Jenkins returned to practice three weeks ago but missed all of preseason and the first five games after injury his shoulder in an Aug. 6 team scrimmage.
"I think it's going to allow Matt and the offense to distribute the ball a little bit differently," Smith said Monday. "I think now, when they try to take certain segments of our offense away, we're going to have more options."
Jenkins has 3,007 yards receiving and 18 touchdowns in 92 career games and 55 starts. Of his 235 catches, 64 percent have converted first downs.
The Falcons (4-1) have a four-game winning streak for the first time since 2004. They've dropped three straight and seven of eight to the Eagles (3-2).
Atlanta, which is tied for No. 2 in NFL rushing, ranks 16th in passing with an average of 221.4 yards per game.