The team said Friday that Burleson (ankle) and Follett (concussion) did not practice and will not play at Minneapolis.
Quarterback Matthew Stafford (right shoulder) also will not play.
The No. 1 pick in the 2009 NFL draft injured his throwing arm in the season-opening loss at Chicago and missed Week 2 against Philadelphia. Stafford missed six games last year with an injured left shoulder and right knee.