HOUSTON (AP) — Hunter Pence drove in Lance Berkman with a double in the 11th inning and the Houston Astros beat the San Diego Padres 4-3 on Sunday to snap a three-game losing streak.
Pence and Carlos Lee hit back-to-back homers off Edward Mujica in the sixth and Pedro Feliz drove in the tying run with a sacrifice fly off closer Heath Bell in the ninth.
Ryan Webb (0-1) relieved in the 10th, and Jeff Keppinger led off the 11th by beating out a bouncer that third baseman Chase Headley couldn't handle. Berkman singled to left, but Keppinger was thrown out at third on Jason Michaels' bunt.
Pence then drove a 1-0 pitch to left-center to give Houston its second win in 13 games. Brandon Lyon (2-1) pitched a perfect 11th to earn the win.
Roy Oswalt struck out a season-high nine in eight innings for Houston, but once again got little support. The Astros have scored five runs in Oswalt's 34 innings this season.
Tim Stauffer started for San Diego in place of Kevin Correia, who left the team on Sunday morning after the death of his younger brother in California on Saturday.
Oswalt got off to a fast start, striking out six and retiring 12 in a row after Tony Gwynn's leadoff single. But he got into trouble during a wild fifth that featured Houston manager Brad Mills' ejection for arguing with plate umpire Alfonso Marquez.
Matt Stairs beat out an infield hit and Nick Hundley walked to start the inning. Oswalt then got Jerry Hairston Jr. to ground out and retired Lance Zawadzki on a popup, bringing Stauffer to the plate.
Oswalt thought he threw a knee-high strike on 1-1 count to his counterpart but Marquez called it low, then had a brief exchange with catcher Humberto Quintero. Mills came out and argued with Marquez before heading back to the dugout.
Stauffer hit a two-run double into the left-field corner for his fourth and fifth career RBIs. Gwynn followed with a run-scoring single for a 3-0 lead.
Mills continued to yell at Marquez from the dugout as Tommy Manzella batted, and Marquez tossed him. Mills ran out of the dugout, and he and Marquez continued to argue before crew chief Tim Tschida came in from second base to intervene.
Mujica relieved Stauffer for the sixth and Lee and Pence hit Houston's first consecutive homers of the season.
David Eckstein led off the ninth with a double to left off Houston closer Matt Lindstrom. He advanced on Hundley's groundout, but was thrown out at home when he tried to score on Hairston's bouncer to shortstop Manzella.
Lee started the bottom half with a grounder to the hole at shortstop. Hairston overthrew Adrian Gonzalez, allowing Lee to take second. Kaz Matsui came in to run, went to third on Pence's groundout and scored on Feliz's flyout to deep center.
NOTES: Gonzalez was out of the starting lineup with a sore shoulder. He checked in as a defensive replacement in the bottom of the ninth. ... The Astros hit back-to-back homers for the first time since Sept. 16, 2009, when Geoff Blum and Jeff Keppinger did it against Cincinnati. ... San Diego manager Bud Black had no details about the death of Correia's brother. He said the team would decide later in the week whether to place Correia on the bereavement list.