Madson will start the season as the Phillies' closer while Brad Lidge continues to rehab from offseason knee and elbow surgeries. Hinske connected on a 3-0 pitch.
Hinske singled in the seventh off Chad Durbin and Brooks Conrad hit a tying home run.
Philadelphia starter J.A. Happ capped his Florida exhibition schedule by reaching the 90-pitch plateau for the first time. He allowed two runs on three hits and struggled with his command, walking a spring-high five.
Happ's next appearance will come in an exhibition game in Philadelphia on Saturday against Pittsburgh. He has a 3.06 ERA in six starts.