Holmes, who entered as the fifth-leading scorer in Division I at 22.8 points a game, hit four 3-pointers and Jackson came off the bench to hit six from beyond the arc for the Bears (17-7, 9-0 Mid-Eastern Athletic Conference), who are 6-0 at home this year.
They have won nine straight games.
Morgan State shot 54.8 percent from the field (34-for-62), including 10-for-19 on 3-point attempts (52.6 percent).
Kevin Thompson scored 14 points and had 12 rebounds and Ameer Ali added 10 points and eight rebounds for Morgan State. Sean Thomas had 11 assists.
Travis Wallace led Florida A&M (5-17, 2-7) with 14 points. Christopher Walker added 12 points and Yannick Crowder scored 11 points and had eight rebounds.