-- On Oct. 2, 2014, Vice President Biden, while speaking at Harvard University's John F. Kennedy School of Government, touched off a diplomatic incident after he sounded off on U.S. allies in the fight against the Islamic State -- suggesting they heedlessly gave arms and money to extremists.
"The Turks ... the Saudis, the Emiratis, etc. What were they doing?" he said. "They were so determined to take down [Syrian President Bashar] Assad and essentially have a proxy Sunni-Shia war."
Biden afterward apologized to top officials in Turkey and the United Arab Emirates.
During the same event, Biden also replied to a question from a student who identified himself as the vice president of the student body. "Isn't it a b-tch?" Biden responded. "Excuse me...the vice president thing."
-- On Sept. 16, 2014, Biden, while speaking at an event in Washington, D.C., recalled how when his son was serving in Iraq, troops spoke about the tough housing market back home in the U.S. "People would come up to him and talk about what was happening to them at home in terms of foreclosures, in terms of bad loans ... I mean, these Shylocks who took advantage of these women and men while overseas."
Shylocks is considered an offensive term for Jews by some groups. Biden later apologized for the remarks.
-- On Aug. 14, 2012, Biden told a Virginia crowd, Mitt Romney's plan would "put y'all back in chains."
-- On April 26, 2012, Biden tried to riff on President Theodore Roosevelt's famous quote “Speak softly and carry a big stick; you will go far," by saying, "I promise you, the president has a big stick. I promise you."
-- On Aug. 1, 2011, as a follow up to Democratic Rep. Mike Doyle suggesting that dealing with Tea Party and fiscal conservatives was like negotiating with terrorists, Biden reportedly piled on by saying, “They have acted like terrorists.”
-- On June 26, 2010, Biden called the manager of a custard shop outside of Milwaukee a "smartass" after the man asked him to lower taxes. Biden made the comment after the Kopp’s Frozen Custard shop manager told him that his dessert would be on the house if he lowered taxes. "Why don’t you say something nice instead of being a smartass all the time?" Biden said a few minutes later.
-- On March 23, 2010, an open microphone caught Biden saying, "This is a big f---ing deal" to President Obama during a Washington signing ceremony for the president's health care law.
-- On July 16, 2009, Vice President Biden gave a blunt summation of the administration's approach to stimulus spending: "People, when I say that, look at me and say, 'What are you talking about, Joe? You're telling me we have to go spend money to keep from going bankrupt?" he said at a stop in Virginia. "The answer is yes."
-- On July 5, 2009, in an interview with ABC's "This Week," Biden conceded that the White House team "misread how bad the economy was." His confession came as unemployment hit 9.5 percent, despite the administration's insistence that it would hold to 8 percent with the stimulus plan.
-- On April 30, 2009, Biden gave advice on dealing with swine flu that seemed to contradict President Obama's warning not to panic. Speaking on NBC's "Today," Biden, a longtime Amtrak rider who has commuted for decades daily from Delaware to Washington, D.C., said he wouldn't advise family necessarily against going to Mexico, the source of the H1N1 outbreak, but he wouldn't tell them to get into any small area like a subway car, automobile, classroom or airplane.
"I would tell members of my family, and I have, I wouldn't go anywhere in confined places right now," Biden said. "It's not that its going to Mexico, it's that you are in a confined aircraft when one person sneezes, it goes everywhere through the aircraft. That's me."
-- On March 13, 2009, Biden addressed a former Senate colleague by saying, "An hour late, oh give me a f**king break," after he arrived on Amtrak at Union Station in Washington, D.C. The vice president's expletive was caught on a live microphone.
-- During a Feb. 25, 2009, interview on CBS' "Early Show," Biden encouraged viewers to visit a government-run Web site that tracks stimulus spending. When asked for the site's web address, Biden could not remember the site's "number."
"You know, I'm embarrassed. Do you know the Web site number?" he asked an aide standing out of view. "I should have it in front of me and I don't. I'm actually embarrassed."
-- At a Jan. 30, 2009, swearing-in ceremony of senior White House staff, Biden mocked Chief Justice John Roberts for his presidential oath blunder on Inauguration Day.
"Am I doing this again?" Biden said, after Obama asked him to administer the oath. When Biden was told the swearing-in was for senior staff -- and not cabinet members -- the vice president quipped, "My memory is not as good as Justice Roberts," prompting a stern nudge from Obama.
-- On Inauguration Day, Jan. 20 2009, Biden misspoke when he told a cheering crowd of supporters, "Jill and I had the great honor of standing on that stage, looking across at one of the great justices, Justice Stewart." Justice John Paul Stevens -- not Stewart -- swore Biden in as vice president.
-- When criticizing former GOP nominee John McCain in Athens, Ohio, on Oct. 15, 2008, Biden said, "Look, John's last-minute economic plan does nothing to tackle the number-one job facing the middle class, and it happens to be, as Barack says, a three-letter word: jobs. J-O-B-S, jobs."
-- In a Sept. 22, 2008, CBS interview, Biden misspoke when he said Franklin D. Roosevelt was president when the stock market crashed in 1929.
"When the stock market crashed, Franklin D. Roosevelt got on the television and didn't just talk about the, you know, the princes of greed. He said, 'Look, here's what happened," he said. Herbert Hoover -- not Roosevelt -- was president in 1929, and television had not yet been invented in 1929.
-- During a Sept. 12, 2008, speech in Columbia, Mo., Biden called for Missouri State Sen. Chuck Graham, who is wheelchair-bound, to "stand up."
"Oh, God love ya," Biden said, after realizing his mistake. "What am I talking about?"
-- At a Sept. 10, 2008, town hall meeting in Nashua, N.H., Biden said, "Hillary Clinton is as qualified or more qualified than I am to be vice president of the United States of America. Quite frankly, it might have been a better pick than me."
-- Biden mistakenly referred to Alaska governor Sarah Palin as the "lieutenant governor" of her state during a town hall meeting on Sept. 4, 2008 at George Mason University in Manassas, Va.
"I heard a very, by the way I mean this sincerely, a very strong and a very good political speech from a lieutenant governor of Alaska who I think is going to be very formidable, very formidable not only in the campaign but in the debate," Biden said.
-- Biden said he was running for president -- not vice president -- during a Sept. 1, 2008, roundtable discussion in Scranton, Pa.
"Today is the moment for me as a United States senator running for president to put aside the national politics and focus on what's happening down there," Biden said.
-- Biden referred to John McCain as "George" during his vice presidential acceptance speech on Aug. 27, 2008, at the Democratic National Convention in Denver, Co. "Freudian slip, folks, Freudian slip," he explained.
-- Biden confused army brigades with battalions when speaking about Obama's plan for sending troops to Afghanistan.
"Or should we trust Barack Obama, who more than a year ago called for sending two additional combat brigades to Afghanistan?"
-- During his first campaign rally with Obama as his vice presidential running mate on Aug. 23, 2008, Biden introduced Obama by saying, "A man I'm proud to call my friend. A man who will be the next President of the United States -- Barack America!"
-- On Jan. 31, 2007 -- the day Biden announced his presidential bid -- the Delaware Senator was roundly criticized for calling Obama "the first mainstream African-American who is articulate and bright and clean and a nice-looking guy. I mean, that's a storybook, man."