Trounced in Florida on Tuesday, Gingrich had just a few days to regroup in Nevada, a state that front-runner Mitt Romney won when he sought the GOP nomination in 2008.
Gingrich is skipping the traditional candidate victory party Saturday night and planning to issue a statement on the outcome.
The former House speaker has a sparse campaign operation in Nevada and took part in just five public events before caucus-goers were set to begin. Neither Gingrich nor a political action committee backing him ran television ads in the state.
In an interview Friday with Fox News, Gingrich said he hopes to defeat Paul's strong Nevada organization to claim second place. Romney too is well-organized here and will pull considerable support from his fellow Mormons.
"We expect Governor Romney to come in first," Gingrich told Fox. "There's a very large Mormon population here."
Gingrich faces a tough road in February. The election calendar includes several states favorable to Romney.
Nevada has been hit hard by the housing meltdown and high jobless rates. Gingrich has touted his tax plan, which he says would spur the economy.
Gingrich used a speech at a country music club to blister Romney, calling the former Massachusetts governor "Obama lite." He argued that Romney's polices are not substantially different than those of the Democratic President Barack Obama.