A proposed state ballot measure would require doctors to be randomly subjected to drug and alcohol testing.
The San Francisco Chronicle reports the so-called "Pee in the Cup" initiative is being pushed by Bob Pack, a technology mogul and former executive at AOL and NetZero.
Pack's campaign, already armed with $2 million in funding, will be launched this summer. He is touting a new poll showing 85 percent of California voters would support random testing of physicians.
The newspaper says the initiative might also seek to lift the cap on damages in medical malpractice cases.
The goal is to get the measure on the November 2014 ballot.
A spokesperson for the California Medical Association calls the effort by Pack a "publicity stunt."