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IVF Unrelated to Giuliana Rancic’s Breast Cancer, Doctor Says

The hormone treatments that E! News host Giuliana Rancic has been receiving in an attempt to get pregnant are probably unrelated to her recent diagnosis of breast cancer, said one doctor.

“The studies that involve IVF and breast cancer are virtually inconclusive,” said Dr. Cynara Coomer, chief of breast surgery and director of the Comprehensive Breast Center at Staten Island University Hospital.

“It’s probably unrelated since the time frame is too close together. But certainly with the testing she would've gone through helped diagnose the cancer sooner.”

Rancic, 37, has been detailing her attempts to become pregnant on the Style Network in her reality show Giuliana & Bill. She and her husband, Bill Rancic – property developer and winner of the first season of The Apprentice – have tried in vitro fertilization three times.

On Monday, Rancic told NBC’s Today that she went in for a mammogram after the third round of IVF, on the advice of her doctor.

“It’s been a shock. . . A lot of people have been asking, ‘We saw that you went and got IVF, so what happened?’ Are you pregnant?’ But sadly, we’ve had to put that off,” Rancic said.

Coomer said Rancic most likely tried Clomid, a fertility drug, and/or progesterone, a pregnancy hormone.

“She caught it so early, her prognosis is excellent,” Coomer said. “Survival rates are about 95 percent. Essentially, it will be something we consider curable.”

Rancic said she will have surgery this week, followed by six and a half weeks of radiation.

Coomer, who has never treated Rancic, said this most likely means she is having a lumpectomy and not a mastectomy.

“Survival outcomes are the same for a lumpectomy with radiation versus a mastectomy,” Coomer said. “She will do very well with that treatment. There is concern about recurrence or a second breast cancer, but even with mastectomy nothing is guaranteed.”

Rancic said she has not given up on her dream to have a baby.

"I will be OK, because I found it early," Rancic said. "Now I truly believe God was looking out for me. . . Had I gotten pregnant, a few years down the line I could have been a lot sicker. So this baby saved my life."

NewsCore contributed to this article.