Some of the greatest casts in television history are reuniting on Feb. 21 to pay tribute to legendary TV director James Burrows, and if the new promo is any indication, we’re in for one hilarious night!

Burrows had a hand in many iconic sitcoms, including "Cheers," "Frasier," "Taxi," "Will & Grace," "Mike & Molly," and "The Big Bang Theory," but the reunion that everyone’s talking about is, of course, the cast of "Friends." Five of the six major cast members (Matthew Perry was in London for a play) gathered to talk about Burrows, discuss their time on the show, and apparently, answer some risque questions.

WATCH: A 'Friends' Reunion Is Finally Happening! Get the Details

“Did you all sign contracts saying that you wouldn’t sleep with each other?” asks host Andy Cohen in the clip.

“David, say something!” Lisa Kudrow implores, as Schwimmer stumbles over his response. Must-see indeed!

WATCH: 'Friends' Cast Reunites to the Delight of Kaley Cuoco: 'I Died and Went to Heaven'

Schwimmer was more eloquent in his responses when he spoke to ET about the reunion at the premiere of FX's "The People v. O.J. Simpson: American Crime Story" last week.

"It was just lovely to all be in the same room,” said the actor, who plays Simpson’s attorney and friend, Robert Kardashian, in the record-breaking miniseries.

Schwimmer also had nothing but praise for Burrows, who directed the pilot episode of the long-running NBC sitcom, as well as a number of other episodes over the first four seasons.

"He is a prolific director and he really, really helped forge the cast as an ensemble," Schwimmer shared. "He really clarified all those relationships from the get go."

"Must See TV: An All-Star Tribute to James Burrows" airs Feb. 21 on NBC.

WATCH: David Schwimmer on 'Friends' Cast Reunion: 'It Was Lovely to All Be in the Same Room'