Rosie O'Donnell is leaving "The View" for a second time.

Her publicist, Cindi Berger, said Friday that the outspoken co-host of the ABC daytime chat show is exiting next week to focus on her five children after the breakup of her marriage.

Berger says O'Donnell and Michelle Rounds, her wife of three years, split in November.

The 52-year-old O'Donnell had returned to "The View" only last summer. Her initial yearlong stay ended stormily in 2007.

Now in its 18th season, the program recently was the target of rumors that a fellow panelist, Rosie Perez, had left for good to appear in a new Broadway play. But she returned this week.

Moderator Whoopi Goldberg and Nicolle Wallace remain with Perez on the show, which was created by Barbara Walters in 1997.